Injections done intraperitoneally: “The resulting slurry was thoroughly and constantly stirred while portions were removed for injection, with 25 gauge needles, intraperitoneally into rats.”

Yes! This article was heavily biased.
They don’t want doctors recommending it because they can’t make $$$$$ from it.
You can by 200 5 mg. pills for about $15 on eBay.
Many people recommend the Advanced Research brand.

I believe the highest recommended dose for bipolar is 40 mg. (8 tablets) per day.
I have to take that all at once when I have really high anxiety. (Mostly in the morning.)
40 mg. (elemental – 5 mg. x 8 pills) calms me down in about 30 minutes or less.
I’m trying to find out what the maximum SAFE dosage is for lithium orotate.

Note: 120 mg. is about 5 mg. of elemental.
So the dosages are often confusing.
If they are saying a dosage over 100, they mean 120/pill. Not 5 mg. Elemental.
Elemental is rarely over 40 mg.

(This article was supposed to be about dosage.)

Thanks Alice,
This helps a Lot! 👍🏼

Fantastic reply!

Right about the article and it’s balance, mostly. The problem is that it didn’t investigate the hazard of Lithium Carbonate enough, the extensive blood testing needed to be done while on it, the rates of excessive kidney damage from it. The lack of patentability of lithiums, and how the law disincentivizes any further studies for lithium as treatment for mental illness. It mentions the last study was a collection of anecdotes in ’87- but why is that? Why doesn’t anyone sponsor further studies? That issue is ignored. There may be no conspiracy of Big Pharma, but maybe of “Big Healthcare” including the FDA. Or just outrageous neglect by healthcare providers! There’s a refusal to look behind the Wizard of Oz’s curtain here, metaphorically speaking. Shouldn’t studies be done just to check on safer alternatives to Lithium Carbonate, even if it isn’t profitable in the near term? People SHOULD be getting angry, just not at the article.

correction, you called Lithium Carbonate, “aspartate”. And another correction: it is not unpatentable because it is “natural”. It is because the patents that covered Lithium Carbonate expired long ago, and I believe the others would be covered by those patents. There is a slight chance that a new, complicated delivery method of medicating with lithium is patentable, be the availability of much cheaper generic lithium, and lithium oratate available as a supplement, makes it unlikely to ever be profitable.

I totally agree, I was a mental health worker for five years and my father worked at a psychiatric hospital and my ex-wife of 8 years took it, even went toxic and returned to it because the replacement depakote didn’t work. The ’78 study conclusion mentioned here is TOTALLY speculative about why 3x the amount was found in rat brains. Fact is, oratate is a kind of transporter that encourages absorption of lithium ions into the human body, and carbonate does nearly the opposite, meaning much higher doses are needed, and therefore side effects from the lithium itself are also worse. Oratate requires much less lithium ions are necessary,, and kidney damage reduced. Not to mention, the kidney damage of CARBONATE hasn’t stopped doctors from prescribing and studies on 10 to 30 years of continual use in patients causes extensive damage in most, many patients needing to discontinue Lithium Carbonate because of how extensive the damage is. Meaning there is a little mini industry in medicine, taking blood tests to guard against toxicity and kidney damage from long-term use. For this to be made into a reason to not use Lithium Oratate, but let doctors continue to prescribe Lithium Carbonate is an outrage